Knjaževac wine-growing region is located in the area around the upper course of the Timok River and surrounded by mountains.

Knjaževac wine-growing region includes the territory of the municipalities of Zaječar and Knjaževac.

Knjaževac wine-growing region occupies an area of 177 805.70 hectares, where the largest wine-growing subregion is Zaječar wine-growing subregion.

Bor wine-growing subregion occupies the north western part of Knjaževac area in the vicinity of Bor and represents the eastern and southeastern slopes of the mountain Crni Vrh.

Bor wine-growing subregion covers parts of municipalities Krivelj, Bučje, Oštrelj, Donja Bela Reka, Slatina, Metovnica, Šarbanovac, Sumrakovac, Podgorac II, Zlot I, Zlot II, Zlot III, Zlot IV, Zlot V, Brestovac and Bor I.

Boljevac wine-growing subregion occupies hills the left and right sides of the Crni Timok and consists of the two separate parts.

Boljevac wine-growing subregion covers the following municipalities:

Northern part: parts of municipalities Podgorac II and Sumrakovac.

Southern part: parts of municipalities Savinac, Dobrujevac, Valakonje, Boljevac, Ilino, Mirovo and Mali izvor, as well as the municipalities Osnić and Vrbovac.

Zaječar wine-growing subregion covers the hills around the upper basin of the Timok and lower basins of the White and the Black Timok and consists of four parts separated by these flows.

Zaječar wine-growing subregion covers the following municipalities:

Northwestern part: parts ofmunicipalities Metriš, Klenovac, Brusnik, Tabakovac, Velika Jasikova, Salaš, Glogovica, Dubočane, Mala Jasikova, Velika Jasikova, Koprivnica, Trnavac, Jelašnica, Rgotina, Vražogrnac, Zaječar, Zvezdan and Nikoličevo.

The northeastern part: parts of municipality Veliki Jasenovac, Gradskovo, Halovo, Veliki Izvor, Prlita, Grljan and Vratarnica, as well as municipalities Mali Jasenovac and Šipikovo.

The southwestern part: parts of municipalities Gamzigrad, Zvezdan, Zaječar, Grljan, Grlište, Vratarnica, Zagrađe, Borovac, Vrbica, Marinovac, Gornja Bela Reka, Lenovac, Lasovo, Bačevica, Dobro Polje, Planinica and municipalities Šljivar and Lubnica.

Potrkanj wine-growing subregion includes upper and middle stream of the Beli Timok, on the slope of about Knjazevac, and consists of three parts.

Potrkanj wine-growing subregion covers the following municipalities:
The western part: parts of municipalities Koželj, Drenovac, Trnovac, Debelica, Manjinac, Ravna, Donja Sokolovica, Stogazovac, Potrkanje, Štipina, Kaličina, Vina, Zorunovac, Slatina, Šuman Topla, Vasilj, Orešac, Balanovac, Rgošte, Glogovac, Grezna, Knjaževac, Kaličina and municipalities Lepena, Drečinovac, Valevac and Bulinovac.

The eastern part: parts of municipalities Vitkovac, Petruša, Jakovac, Jelašnica, Donje Zuniće, Berićinovac, Knjaževac and Trgovište.

Southern part: parts of municipalities Knjaževac, Trgovište, Crvenje and Žlne.